The effects of antioxidative treatment upon electrolyte and metabolic reactions of a chronically stressed group



Abstract. The staff of a rehabilitation clinic was treated with an antioxidative nutra- ceutical during a demanding time of 8 weeks in a double blind, placebo controlled manner. Metabolic changes in metabolism and elec- trolyte state due to chronic workload, acute, standardized ergometry and, eventually to antioxidant treatment were recorded by cap- illary blood determination of pH, pCO2, BE, blood glucose, lactate, K, Ca, Mg by Clini- cal Stress Assessment software. It turned out that those parameters changed significantly after 8 weeks of increased workload and also after standard ergometry. However, the anti- oxidant treated group showed significantly less chronic signs of metabolic distress due to the demanding working situation as well as a significantly calmer reaction to acute ergo– metric load, concerning lactate, base excess and pCO2 changes. Electrolyte changes figure prominently among the workload effects both in group averages and in treatment dependent correlations with metabolic data. Mg changes are particularly sensible to a rise in metabolic dynamics, and therefore Mg is liable to be substituted to grant undisturbed energy turn- over in a difficult situation.